- Title
- Cortical thickness and subcortical brain volumes in professional rugby league players
- Creator
- Wojtowicz, Magdalena; Gardner, Andrew J.; Stanwell, Peter; Zafonte, Ross; Dickerson, Bradford C.; Iverson, Grant L.
- Relation
- NeuroImage: Clinical Vol. 18, p. 377-381
- Publisher Link
- http://dx.doi.org/10.1016/j.nicl.2018.01.005
- Publisher
- Elsevier BV
- Resource Type
- journal article
- Date
- 2018
- Description
- Purpose: The purpose of this study was to examine cortical thickness and subcortical volumes in professional rugby players with an extensive history of concussions compared to control subjects. Method: Participants included 24 active and former professional rugby league players [Age M(SD) = 33.3(6.3); Range = 21–44] with an extensive history of concussion and 18 age- and education-matched controls with no history of neurotrauma or participation in contact sports. Participants underwent T1-weighted imaging and completed a neuropsychological battery, including two tests of memory. Whole brain cortical thickness analysis and structural volume analysis was performed using FreeSurfer version 6.0. Results: Professional rugby league players reported greater alcohol consumption (p < .001) and had significantly worse delayed recall of a visually complex design (p = .04). They did not differ from controls on other clinical outcome measures. There were no differences in cortical thickness between the groups. Professional players had smaller whole brain (p = .003), bilateral hippocampi (ps = .03), and left amygdala volumes (p = .01) compared to healthy controls. Within the players group, there were significant associations between greater alcohol use and smaller bilateral hippocampi and left amygdala volumes. There were no associations between structural volumes and history of concussions or memory performance. Conclusions: The literature examining cortical thickness in athletes with a history of multiple concussions is mixed. We did not observe differences in cortical thickness in professional rugby league players compared to controls. However, smaller subcortical volumes were found in players that were, in part, associated with greater alcohol consumption.
- Subject
- volumetric MRI; cortical thickeness; concussion; brain morphometry; athletes; rugby
- Identifier
- http://hdl.handle.net/1959.13/1448747
- Identifier
- uon:43477
- Identifier
- ISSN:2213-1582
- Rights
- © 2018 Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/BY-NC-ND/4.0/).
- Language
- eng
- Full Text
- Reviewed
- Hits: 1281
- Visitors: 1437
- Downloads: 157
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | ATTACHMENT02 | Publisher version (open access) | 332 KB | Adobe Acrobat PDF | View Details Download |